Covers the molecular and cellular events of development from fertilized egg to adult. Genetic basis of body form, cell fate specification and differentiation, processes controlling morphogenesis, growth, stem cells and regeneration will be examined. Differential gene regulation, intercellular signaling and their evolutionary conservation will be central to discussion of mechanisms governing developmental processes. Additional topics: developmental plasticity, impact of epigenetic and environmental factors, and basis of disease gleaned from developmental biology research. Live embryos will complement and reinforce concepts covered in class. Enrollment limited to 36. Expected: BIOL 0200 (or equivalent), and one course in genetics, cell biology or embryology.
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