Examines organelles and macromolecular complexes of eukaryotic cells with respect to structural and functional roles in major cellular activities. Emphasizes experimental basis for knowledge in modern cell biology using original literature, and discusses validity of current concepts. For advanced undergraduates and beginning graduate students. Complementary to BIOL 1270 and 1540. Prerequisites: BIOL 0280, 0470, 0500, or instructor permission. Graduate students register for BIOL 2050.